My brother lives in Ann Arbor and I was fortunate enough to catch a Sox/Tigers game last year and I have to tell you, that place is amazing. I haven't been to too many parks (The Cell, Old Comiskey, Miller and Wrigley) and I'd have to put Comerica at #1 on my list. It's not in the best of neighborhoods, in fact it's in the ghetto, but about 95% of Detroit is a ghetto. It's just such a beautiful place to check out a game. And I'd also like to say that the Tigers fans are actually a good group of folks. Very nice people, but I guess you'd have to be if your team was so horrid. There were also a TON of White Sox fans. I guarantee a good time man, that park is fantastic.
Just one thing, stay away from the Little Ceasar's Pizza.